MAPS-2 Study

The Metoclopramide for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a single-blind, randomized controlled trial of metoclopramide for the prevention of pneumonia in patients with dysphagia after an acute stroke

IRAS 290474 CPMS 50728 Twitter @MAPS2trial

The aim is to test whether giving metoclopramide 10 mg three times a day for 14 days prevents pneumonia and death after acute stroke.

Please click RANDOMIZE to randomize a participant and enter/edit data. It will take you to the RedCap site.

Please click STUDY DETAILS for a protocol summary, the EOI form, the study team, and our newsletters.

If you have had green light to open the study you will have to authorize your local team on the Redcap Website. You will need the invitation email you have been sent with the temoprary password.

Please watch this video to show how to give metoclopramide/saline administration via the nasogastric tube.

We have 375 participants and 63active centres plus 2 repatriation sites.

  1. Stoke-on-Trent 24.02.22 (Dr Anushka Warusevitane Ass PI Dr Sushanth Shankar) [81]
  2. Durham 19.5.22 (ANP Michelle Matthews) [18]
  3. Bournemouth, Royal Bournemouth Hosptial 12.10.22 (Dr Katharine Fairbairn Ass PI Anthony Smith) [17]
  4. Exeter Royal Devon and Exeter 9.6.22 (Prof Martin James) [16]
  5. Nottingham, Queen’s Medical Centre 24.10.22 (Dr Senthil Raghnathan) [16]
  6. Truro, Royal Cornwall Hosptial 21.8.22 (Dr Katja Adie) [15]
  7. Bury St Edmunds, West Suffolk Hopsital 3.5.22 (Dr Abdul Azim) [14]
  8. Southhampton University Hospital 10.8.22 (Dr Shivaprasad Siddegowda, Ass |PI Dr Ahmed Elserafy) [14]
  9. Chester, Countess of Chester 12.07.22 (PI Prof Kausik Chatterjee, Ass PI Dr Pramodh Hettiarachchi) [13]
  10. Cambridge, Addenbrooks University Hospital 27.7.22 (Dr Kayvan Khandjooi) [11]
  11. London, Northwick Park Hospital 28.7.22 (Dr Aravinth Sivagnanaratnam) [10]
  12. Leicester, University Hosptial 15.9.22 (Dr Kashif Musarrat) [9]
  13. Aberdeen 4.4.22 (Dr German Guzman Gutierrez Ass PI Dr Hazel Thompson) [8]
  14. Newcastle upon Tyne, Royal victoria Hosptial 15.02.23 (Dr Michelle Davis) [8]
  15. Taunton, Musgrove Park Hospital 12.9.22 (Dr Babu Pusuluri) [8]
  16. London, Royal London Hosptial (Dr Oliver Spooner) [8]
  17. Crewe, Leighton Hospital 11.11.22 (Mrs Holly Maguire) [7]
  18. Luton and Dunstable University Hosptial 7.12.22 (Dr Lakantha Alvis) [7]
  19. Leeds Teaching Hosptials 4.11.22 (Dr Vasileios Papavasileiou, AssPI Dr Rebecca Tremain) [7]
  20. Stockton-on-Tees, University Hosptial of North Tees 24.01.23 (Dr Sarah Whitehouse) [6]
  21. Swansea, Morriston Hosptial 11.5.22 (Dr Peter Slade) [5]
  22. Birmingham, University Hosptial of Birmingham 7.11.22 (Dr Mark Wilmot) [5]
  23. Carlisle North Cumbria Integrated Care NHSFT 6.3.23 (Dr Rachel Glover) [5]
  24. Sunderland, Royal Sunderland Hospital 29.4.22 (Dr Naweed Sattar) [5]
  25. Whiston St Helens and Knownsley 4.3.22 (Dr Sunanda Mavinamane) [5]
  26. Northampton General Hospital NHS Trust 26.09.22 (Dr Venkatesan Srinivasan) [4]
  27. Wolverhampton New Cross Hosptial 8.8.22 (Dr Nasar Ahmad) [4]
  28. Aberystwyth Bronglais Hospital 10.5.22 (Dr Syed Abid Raza) [4]
  29. Middlesborough, James Cook Hosptial 27.6.22 (Mr Andrew Young) [4]
  30. Carmarthen Glangwili GH 31.05.22 (Dr Pagdala Sridhar) [4]
  31. London St George’s12.04.2023 (Dr Youssif Abousleiman) [4]
  32. London, King’s College 3.5.2023 (Dr Rohan Pathansali) [3]
  33. Glasgow Royal Infirmary 12.9.22 (Prof Terry Quinn) [3]
  34. Glasgow, Monklands 27.06.22 (Dr Mark Barber) [3]
  35. Belfast, Royal Victoria Hospital 12.10.22 (Dr Patricia Fearon) [3]
  36. Hairmyres, Lanarkshire 5.5.23 (Dr Philip Birschel) [3]
  37. London, Imperial College Charing Cross Hosptial 4.5.2023 (Dr Abid Malik) [3]
  38. Dundee, Ninewells Hosptial 28.11.22 (Dr Matt Lambert) [2]
  39. Milton Keynes University Hopstial NHS FT 1.9.22 (Dr Yousif Behnam) [2]
  40. Watford West Hertfordsire TH 27.2.22 (Dr Mohit Bhadari) [3]
  41. York 5.6.2023 (Dr Luke Bridge) [1]
  42. Derby, University Hosptials of Derby and Burton 13.01.23 (Dr Tim England) [1]
  43. Llanelli Prince Philip 30.3.22 (Dr Senthil Kumar) [1]
  44. Liverpool Arrowe Park Wirral University Hospitals NHS FT 18.11.22 (Dr Ruth Davies) [1]
  45. Huddersfield, Calderdale and Huddersfield NHS FT 27.01.23 2022 (Dr Syed Ahmad) [1]
  46. Wansbeck Northumbria NHS FT 9.5.23 (Ms Anna Smith) [1]
  47. London, UCLH 3.8.2023 (Dr Richard Perry) [1]
  48. Norwich, Norfolk and Norwich University Hospitals NHS FT 21.6.22 (Dr Joyce Balami)
  49. Gateshead Queen Elizabeth Hosptial 8.3.23 (Ms Bev McClelland)
  50. Dorchester Dorset County H 23.03.23 (Dr Halald Proeschel)
  51. Doncaster 23.05.2023 (Dr Dinesh Cahdha)
  52. Sheffield Royal Hallamshire Hospital (DR Ali Ali)
  53. Antrim, Northern Healthcare Trust NI 23.05.2023 (Dr Murudappa Bhattad)
  54. Southern Health and Social Care Trust NI 6.6.23 (Dr Michael McCormick)
  55. Manchester/Salford Northern Care Alliance FT 16.06.2023 (Prof Craig Smith)
  56. Bradford Teaching Hospital NHS FT 27.06.2023 (Dr Numan Khan)
  57. Epsom and St Helier 27.06.2023 (Dr Puneet Kakar)
  58. Ulster, Northern Ireland SE HSCT 30.08.2023 (Dr Mark Bowman)
  59. Colchester Hosptital (5.9.23) (Dr Ramachandran Sivakumar)
  60. Enniskillen South West Acute Hosptital 07.09.2023 (Dr Breffni Keegan)
  61. Fife, Victoria Hosptial (11.09.2023) (Dr Vera Cvoro)
  62. Liverpool University Hospitals NHSFT 11.09.2023 (Dr Thant Hlaing)
  63. Hull University Hosptial 27.09.23 (Dr Bernard Esisi)
  64. Chelmsford, Broomfield Hospital 28.09.23 (Dr Ramanathan Kirtivasan)

Sites closed

Sandwell Hospital 1.11.22 (Dr Sissi Ispoglou) Closed 1 Mar 2023