MAPS-2 Study

The Metoclopramide for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a single-blind, randomized controlled trial of metoclopramide for the prevention of pneumonia in patients with dysphagia after an acute stroke

IRAS 290474 CPMS 50728

The aim is to test whether giving metoclopramide 10 mg three times a day for 14 days prevents pneumonia and death after acute stroke.

Please click RANDOMIZE to randomize a participant and enter data. It will take you to the RedCap site.

Please click STUDY DETAILS for a protocol summary, the EOI form, the study team, and our newsletters.

If you have had green light to open the study you will have to authorize your local team on the Redcap Website. You will need the invitation email you have been sent with the temoprary password.

Please watch this video to show how to give metoclopramide/saline administration via the nasogastric tube.

We have 152 participants and 42 active centres.

  1. Stoke-on-Trent 24.02.22 (Dr Anushka Warusevitane Ass PI Dr Sushanth Shankar) Last recruited 11/02/2023 [49]
  2. Chester, Countess of Chester 12.07.22 (PI Prof Kausik Chatterjee, Ass PI Dr Pramodh Hettiarachchi) [9]
  3. Exeter Royal Devon and Exeter 9.6.22 (Prof Martin James) [8]
  4. Bury St Edmunds 3.5.22 (Dr Abdul Azim) [7]
  5. Bournemouth, Royal Bournemouth Hosptial 12.10.22 (Dr Katharine Fairbairn) [7]
  6. Truro, Royal Cornwall Hosptial 21.8.22 (Dr Katja Adie) [7]
  7. London, Northwick Park Hospital 28.7.22 (Dr Aravinth Sivagnanaratnam) [7]
  8. Aberdeen 4.4.22 (Dr German Guzman Gutierrez Ass PI Dr Hazel Thompson) last recruited 08/02/2023 [6]
  9. Durham 19.5.22 (ANP Michelle Matthews) [6]
  10. Southhampton, University Hospital Southampton 10.8.22 (Dr Shivaprasad Siddegowda) [6]*
  11. Aberdeen 4.4.22 (Dr German Guzman Gutierrez Ass PI Dr Hazel Thompson) [5]
  12. Whiston St Helens and Knownsley 4.3.22 (Dr Sunanda Mavinamane) [4]
  13. Cambridge, Addenbrooks University Hospital 27.7.22 (Dr Kayvan Khandjooi) [3]
  14. Leeds Teaching Hosptials 4.11.22 (Dr Vasileios Papavasileiou, AssPI Dr Rebecca Tremain) [3]
  15. Glasgow Royal Infirmary 12.9.22 (Prof Terry Quinn) [3]
  16. Sunderland, Royal Sunderland Hospital 29.4.22 (Dr Naweed Sattar) [3]
  17. Taunton, Musgrove Park Hospital 12.9.22 (Dr Babu Pusuluri) [2]
  18. Middlesborough, James Cook Hosptial 27.6.22 (Mr Andrew Young) [2]
  19. Wolverhampton New Cross Hosptial 8.8.22 (Dr Nasar Ahmad) [2]
  20. Crewe, Leighton Hospital 11.11.22 (Mrs Holly Maguire) [2]
  21. Leicester, University Hosptial 15.9.22 (Dr Kashif Musarrat) [2]
  22. Nottingham University Hospital 24.10.22 (Dr Senthil Raghnathan) [2]
  23. Northampton General Hospital NHS Trust 26.09.22 (Dr Venkatesan Srinivasan) [2]
  24. Swansea 11.5.22 (Dr Peter Slade) [2]
  25. Dundee NHS Tayside 28.11.22 (Dr Matt Lambert) [1]
  26. Belfast Health and Social Care Trust 12.10.22 (Dr Patricia Fearon) [1]
  27. Birmingham, University Hosptial of Birmingham 7.11.22 (Dr Mark Wilmot) [1]
  28. Huddersfield, Calderdale and Huddersfield NHS FT 27.01.23 2022 (Dr Syed Ahmad) [1]
  29. London Barts Health Royal London, Newham and Whipps Cross 1.6.22 (Dr Oliver Spooner) [1]
  30. Luton and Dunstable University Hosptial 7.12.22 (Dr Lakantha Alvis) [1]
  31. Llanelli Prince Philip 30.3.22 (Dr Senthil Kumar) [1]
  32. Milton Keynes University Hopstial NHS FT 1.9.22 (Dr Yousif Behnam) [1]
  33. Aberystwyth Bronglais Hospital 10.5.22 (Dr Syed Abid Raza) [1]
  34. Glasgow, Monklands 27.06.22 (Dr Mark Barber) [1]
  35. Carmarthen Glangwili GH 31.05.22 (Dr Pagdala Sridhar)
  36. Norwich, Norfolk and Norwich University Hospitals NHS FT 21.6.22 (Dr Joyce Balami)
  37. Sandwell Hospital 1.11.22 (Dr Sissi Ispoglou) Closed 1 Mar 2023
  38. Liverpool Arrowe Park Wirral University Hospitals NHS FT 18.11.22 (Dr Ruth Davies)
  39. Derby, University Hosptials of Derby and Burton 13.01.23 (Dr Tim England)
  40. North Tees and Hartlepool NHS FT 24.01.23 (Dr Sarah Whitehouse)
  41. Newcastle upon Tyne NHS FT 15.02.23 (Dr Michelle Davis)
  42. Gateshead Queen elizabeth Hosptial 8.3.23 (Ms Bev McClelland)